[BME Seminar] Bioelectronics: From Biosensors to Electrical Therapy

ON2023-01-29TAG: ShanghaiTech UniversityCATEGORY: Lecture

Speaker: Dr. LI Chenzhong, Professor of Biomedical Engineering and Biochemistry at Tulane University School of Medicine

Date and time: 20:00-21:30, February 3 (Beijing Time)

Venue: Zoom Meeting

Meeting ID: 588 380 5942  Password: zyTyX0


Bioelectronics is referred to as an integration of biomolecules and electronic elements that combines diagnostics and therapeutics, aiming for biomolecular detections and manipulations, which would be a key part of “smart” medicine. Various biomolecules exhibit their intrinsic biological electrical properties such as redox potentials, charge transfer rate, membrane potential, impedance, etc. On the other hand, the unique electronic, optical, physical, and catalytic properties of engineered nanomaterials and biomaterials provide new strategy of combining Bio and Electronics together to yield functional devices such as biosensors. In Dr. LI's lab, we aim to integrate nanomaterials and biomolecules with MEMS technology, IoTs, and analytical systems to develop highly sensitive miniaturized analytical instruments for biomedical sensing and noninvasive medical therapy.

This lecture will outline our recent research activities for the fundamental study of physical and electrical properties of cells, as well as the development of a new generation of Point of Care Testing devices and cell/organs on chips. By recapitulating the multicellular architectures, cell-cell interfaces, and physicochemical microenvironments, these devices enable high-resolution, real-time sensing and in vitro analysis of biochemical, genetic, and metabolic activities of living cells/tissues in a functional tissue and organ context. Several newly developed bioelectronic platforms will be introduced including: 1) Biosensors for neuron chemical mapping; 2) Organ-on-a-chip for whole cell analysis and manipulation. The biosensors can monitor crucial cell signaling networks and cell metabolic pathways, as well as detect diseases in their earliest stage, titrating drug effects and enabling worldwide remote diagnosis.


Dr. LI Chenzhong is the professor of Biomedical Engineering and Biochemistry at Tulane University School of Medicine. Prior to joining Tulane, Dr LI is the Worlds Ahead Professor and the Director of Nanobioengineering/Bioelectronics Center of the Department of Biomedical Engineering at Florida International University. He is the former Program Director of NSF overseeing biosensors and biomedical devices research and managed several hundreds of research projects in the field nationwide.

Dr. LI is an expert in bioinstrumentation, specifically in the development of biomedical devices for both diagnostic and therapeutic, which could also have cross-applications for environmental, food safety monitoring, agriculture, and homeland security. Dr. LI’s research interests include biosensors, Point Care of Testings, cell/tissue electronics, neuron-device interface, cell/organ on a chip, electric therapy, as well as electron transfer study of various biomaterials. The impact of his work is documented in 17 granted patents, about 170 journal papers, and 3 startup companies since 1993, in China, Canada and the USA.

Dr LI is the co-Editor-in-Chief of the journal Biosensor and Bioelectronics and the deputy editor of journals Reasearch (AAAS) and Biosensors (MDPI). He is an elected fellow of the American Institute for Medical and Biological Engineering (AIMBE) and a fellow member of National Academy of Inventors (NAI).